CPSF6 (cleavage and polyadenylation specific factor 6. 68kDa)

GWB-8369EF

1:1562500

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. CPSF6 is one subunit of a cleavage factor required for 3` RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3` end processing complex and facilitates the recruitemeSummary: The protein encoded by this gene is one subunit of a cleavage factor required for 3\' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3\' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This protein is the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. Summary: The protein encoded by this gene is one subunit of a cleavage factor required for 3\' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3\' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This protein is the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. Rual. J. F. . (2005) Nature 437 (7062). 1173-1178.