SURF6 (surfeit 6)

GWB-647F1D

1:312500

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. This gene is located in the surfeit gene cluster. a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene. being ubiquitously expressed. and the encoded protein has been localized tSummary: This protein is located in the surfeit gene cluster a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene being ubiquitously expressed and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties based on characteristics determined in mouse. Summary: This protein is located in the surfeit gene cluster a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene being ubiquitously expressed and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties based on characteristics determined in mouse. Magoulas. C. Gene 243 (1-2). 115-123 (2000).