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C14ORF156

C14ORF156

Item no.	18-003-44231
Manufacturer	GENWAY
Amount	0.05 mg
Category	Oncology Antibodies Western Blot Primary Antibodies By Organ Testicular & Prostate Cancer
Type	Antibody
Applications	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-95CB6F
Similar products	18-003-44231
Available
Genway ID:	GWB-95CB6F
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human C14orf156. Western Blot: Suggested dilution at 0. 5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50. 000 - 100. 000 as second antibody.
ELISA Titre:	1:312500
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. As a RNA-binding protein. C14orf156 acts as a nuclear receptor corepressor. It probably acts by binding the SRA RNA. and repressing the SRA-mediated nuclear receptor coactivation. C14orf156 binds the STR7 loop of SRA RNA. It is also able to repress glucoc
Function:	RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR) androgen (AR) thyroid (TR) and VDR-mediated transactivation.
Subcellular Location:	Mitochondrion. Nucleus. Note=Predominantly mitochondrial. Some fraction is nuclear. In the nucleus it is recruited to nuclear receptor target promoters.
Tissue Specificity:	Ubiquitously expressed with highest level in heart liver skeletal muscle and testis.
Similarity:	Contains 1 RRM (RNA recognition motif) domain. Summary: Steroid receptor RNA activator (SRA or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al. 2006 [PubMed 16762838]). [supplied by OMIM]. Xu. X. . Unpublished (2000).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 9/11/2025

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