CACNB1 (calcium channel. voltage-dependent. beta 1 subunit)

GWB-90C253

1:312500

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. The protein encoded by CACNB1 belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition. increasing peak calcium current. controlling the alpha-1 subunit membrane targeting andSummary: The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition increasing peak calcium current controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. Foell. J. D. . (2004) (er) Physiol. Genomics 17 (2). 183-200.