Comparison

G-protein coupled bile acid receptor 1

Item no. 18-461-10152
Manufacturer GENWAY
Amount 0.05 ml
Category
Type Antibody
Applications IHC
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-FE3CC1
Similar products 18-461-10152
Available
Genway ID:
GWB-FE3CC1
Immunogen:
C-terminal domain of human. Synthetic peptide - KLH conjugated.
Uses: IHC (11 - 27 ug/ml) (Optimal dilution to be determined by the researcher)
Function:
Receptor for bile acid. Bile acid-binding induces its internalization activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Subcellular Location:
Cell membrane; multi-pass membrane protein.
Tissue Specificity:
Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues it is expressed in stomach duodenum ileocecum ileum jejunum ascending colon transverse colon descending colon cecum and liver but not in esophagus and rectum.
Similarity:
Belongs to the G-protein coupled receptor 1 family [view classification]. [1] Kawamata Y. Fujii R. Hosoya M. Harada M. Yoshida H. Miwa M. Fukusumi S. Habata Y. Itoh T. Shintani Y. Hinuma S. et al. A G protein-coupled receptor responsive to bile acids[2] Maruyama T. Miyamoto Y. Nakamura T. Tamai Y. Okada H. Sugiyama E. Nakamura T. Itadani H. and Tanaka K. Identification of membrane-type receptor for bile acids (M-BAR)[3] Maruyama T. Miyamoto Y. Nakamura T. Tamai Y. Okada H. Sugiyama E. Nakamura T. Itadani H. Tanaka K. Identification of membrane-type receptor for bile acids (M-BAR). [4] Kawamata Y. Fujii R. Hosoya M. Harada M. Yoshida H. Miwa M. Fukusumi S. Habata Y. Itoh T. Shintani Y. et al. A G protein-coupled receptor responsive to bile acids. [5] Takeda S. Kadowaki S. Haga T. Takaesu H. Mitaku S. Identification of G protein-coupled receptor genes from the human genome sequence. [6] Strausberg R. L. Feingold E. A. Grouse L. H. Derge J. G. Klausner R. D. Collins F. S. Wagner L. Shenmen C. M. Schuler G. D. Altschul S. F. et al. Generation and initial analysis of more than 15 000 full-length human and mouse cDNA sequences.

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Amount: 0.05 ml
Available: In stock
available

Delivery expected until 10/30/2025 

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