Olfactory receptor OR11-16

N-terminal extracellular domain of human. Synthetic peptide - KLH conjugated.
Uses: IHC (16 ug/ml) (Optimal dilution to be determined by the researcher) Miscellaneous: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry. Summary: Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [1] Wang J. Weng J. Cai Y. Penland R. Liu M. and Ittmann M. et al. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase[2] Xu L. L. Sun C. Petrovics G. Makarem M. Furusato B. Zhang W. Sesterhenn I. A. McLeod D. G. Sun L. Moul J. W. and Srivastava S. Quantitative expression profile of PSGR in prostate cancer[3] Weng J. Ma W. Mitchell D. Zhang J. and Liu M. et al. Regulation of human prostate-specific G-protein coupled receptor PSGR by two distinct promoters and growth factors[4] Weng J. Wang J. Cai Y. Stafford L. J. Mitchell D. Ittmann M. and Liu M. Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers[5] Malnic B. Godfrey P. A. and Buck L. B. et al. The human olfactory receptor gene family[6] Malnic B. Godfrey P. A. Buck L. B. The human olfactory receptor gene family.