RABBIT ANTI ATG12 (INTERNAL REGION)

ATG12 (INTERNAL REGION)

Phosphate buffered saline

Synthetic peptide corresponding to a 15 aa sequence from near the centre of human ATG12.

Required for autophagy. Subunit structureConjugated to ATG5. Subcellular locationCytoplasm By similarity. Tissue specificityUbiquitous. Ref. 1Sequence similaritiesBelongs to the ATG12 family. Sequence cautionThe sequence AAH12266. 2 differs from that shown. Reason: Erroneous initiation. 1. Grigoriadis A. et al. (2006) Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data. Breast Cancer Res. 8: R56. 2. Milz S. et al. (2007) An immunohistochemical study of the triangular fibrocartilage complex of the wrist: regional variations in cartilage phenotype. J Anat. 211: 1-7. 3. Gagarina V. et al. (2008) Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins. J Biol Chem 283: 648-59. [1] \" Characterization of human and mouse cartilage oligomeric matrix protein. \" Newton G. Weremowicz S. Morton C. C. Copeland N. G. Gilbert D. J. Jenkins N. A. Lawler J. Genomics 24:435-439(1994) [PubMed: 7713493] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] VARIANTS ASP-50; TRP-51; GLY-109; GLY-224 AND PRO-285. Tissue: Cartilage. [2] \" Human comp cDNA with 5 SNIPs. \" Hashimoto Y. Mori H. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [MRNA] VARIANTS ASP-50; TRP-51; GLY-109; GLY-224 AND PRO-285. [3] \" The DNA sequence and biology of human chromosome 19. \" Grimwood J. Gordon L. A. Olsen A. S. Terry A. Schmutz J. Lamerdin J. E. Hellsten U. Goodstein D. Couronne O. Tran-Gyamfi M. Aerts A. Altherr M. Ashworth L. Bajorek E. Black S. Branscomb E. Caenepeel S. Carrano A. V. Caoile C. Chan Y. M. Christensen M. Cleland C. A. Copeland A. Dalin E. Dehal P. Denys M. Detter J. C. Escobar J. Flowers D. Fotopulos D. Garcia C. Georgescu A. M. Glavina T. Gomez M. Gonzales E. Groza M. Hammon N. Hawkins T. Haydu L. Ho I. Huang W. Israni S. Jett J. Kadner K. Kimball H. Kobayashi A. Larionov V. Leem S. -H. Lopez F. Lou Y. Lowry S. Malfatti S. Martinez D. McCready P. M. Medina C. Morgan J. Nelson K. Nolan M. Ovcharenko I. Pitluck S. Pollard M. Popkie A. P. Predki P. Quan G. Ramirez L. Rash S. Retterer J. Rodriguez A. Rogers S. Salamov A. Salazar A. She X. Smith D. Slezak T. Solovyev V. Thayer N. Tice H. Tsai M. Ustaszewska A. Vo N. Wagner M. Wheeler J. Wu K. Xie G. Yang J. Dubchak I. Furey T. S. DeJong P. Dickson M. Gordon D. Eichler E. E. Pennacchio L. A. Richardson P. Stubbs L. Rokhsar D. S. Myers R. M. Rubin E. M. Lucas S. M. Nature 428:529-535(2004) [PubMed: 15057824] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [4] Mural R. J. Istrail S. Sutton G. G. Florea L. Halpern A. L. Mobarry C. M. Lippert R. Walenz B. Shatkay H. Dew I. Miller J. R. Flanigan M. J. Edwards N. J. Bolanos R. Fasulo D. Halldorsson B. V. Hannenhalli S. Turner R. Yooseph S. Lu F. Nusskern D. R. Shue B. C. Zheng X. H. Zhong F. Delcher A. L. Huson D. H. Kravitz S. A. Mouchard L. Reinert K. Remington K. A. Clark A. G. Waterman M. S. Eichler E. E. Adams M. D. Hunkapiller M. W. Myers E. W. Venter J. C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [5] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Ovary. [6] \" Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene. \" Briggs M. D. Hoffman S. M. G. King L. M. Olsen A. S. Mohrenweiser H. Leroy J. G. Mortier G. R. Rimoin D. L. Lachman R. S. Gaines E. S. Cekleniak J. A. Knowlton R. G. Cohn D. H. Nat. Genet. 10:330-336(1995) [PubMed: 7670472] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 326-344 VARIANT EDM1 TYR-342 VARIANT PSACH ARG-328. [7] \" Cartilage oligomeric matrix protein is a calcium-binding protein and a mutation in its type 3 repeats causes conformational changes. \" Chen H. Deere M. Hecht J. T. Lawler J. J. Biol. Chem. 275:26538-26544(2000) [PubMed: 10852928] [Abstract]Cited for: PROTEIN SEQUENCE OF 80-89 SUBUNIT CALCIUM-BINDING CHARACTERIZATION OF VARIANT PSACH ASP-469 DEL. [8] \" Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I II and IX. \" Thur J. Rosenberg K. Nitsche D. P. Pihlajamaa T. Ala-Kokko L. Heinegaard D. Paulsson M. Maurer P. J. Biol. Chem. 276:6083-6092(2001) [PubMed: 11084047] [Abstract]Cited for: PROTEIN SEQUENCE CALCIUM-BINDING INTERACTION WITH COLLAGEN I; COLLAGEN II AND COLLAGEN IX CHARACTERIZATION OF VARIANT PSACH ASP-469 DEL CHARACTERIZATION OF VARIANT EDM1 TYR-361. [9] \" Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin. \" Di Cesare P. E. Chen F. S. Moergelin M. Carlson C. S. Leslie M. P. Perris R. Fang C. Matrix Biol. 21:461-470(2002) [PubMed: 12225811] [Abstract]Cited for: INTERACTION WITH FN1. [10] \" Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias. \" Mann H. H. Oezbek S. Engel J. Paulsson M. Wagener R. J. Biol. Chem. 279:25294-25298(2004) [PubMed: 15075323] [Abstract]Cited for: INTERACTION WITH MATN1; MATN3 AND MATN4.