IL-1 BETA


Item no.	18-783-76146
Manufacturer	GENWAY
Amount	0.1 mg
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Western Blot ELISA Primary Antibodies
Type	Antibody
Applications	WB, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-F60E19
Similar products	18-783-76146
Available
Genway ID:	GWB-F60E19
Specificity:	IL-1 BETANCBI
Gene ID:	24494
Isotype:	Polyclonal IgG
Immunogen:	Recombinant rat IL-1 beta
Specificity Note:	This product recognises rat IL-1 beta
Antiserum Preparation:	Antisera to rat IL-1 beta were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by antigen affinity chromatography.
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		None present. Reconstitution: Reconstitute with 0. 1 ml distilled waterSuggested
Dilution:	Suggested
Dilution:	ELISA - 0. 5ug/mlWestern Blotting - 0. 1ug/ml - 0. 2ug/mlFunctional Assays - 0. 09ug/ml - 0. 14ug/ml Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response and is involved in a variety of cellular activities including cell proliferation differentiation and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This protein and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 10/30/2025

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