GAP43


Item no.	18-783-76699
Manufacturer	GENWAY
Amount	0.1 ml
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Development Antibodies Western Blot Primary Antibodies
Type	Antibody
Applications	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-728FAA
Similar products	18-783-76699
Available
Genway ID:	GWB-728FAA
Specificity:	GAP43 NCBI
Gene ID:	2596
Specificity:	GAP43
Immunogen:	Synthetic phosphopeptide corresponding to an amino acid sequence within GAP-43 which includes phosphorylated Ser41.
Specificity Note:	This product is specific for Growth Associated Peptide 43 (GAP-43) when phosphorylated at serine 41. GAP-43 is expressed in neuronal growth cones during development and during axonal regeneration and is phosphorylated at Ser41 by protein kinase C.
Antiserum Preparation:	Antisera to phosphorylated GAP-43 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution:	10mM HEPES pH7. 5
Preservative Stabilisers:		0. 09%Sodium Azide0. 01%Bovine Serum Albumin50%GlycerolSuggested
Dilution:	Western Blot: This product detects a band of approximately 50kDa in rat cortex lysates. Suggested
Dilution:	Western Blotting - 1:1000
Function:	This protein is associated with nerve growth. It is a major component of the motile \" growth cones\" that form the tips of elongating axons.
Subunit:	Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence (By similarity).
Subcellular Location:	Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction synapse. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes.
Ptm:	Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.
Similarity:	Belongs to the neuromodulin family.
Similarity:	Contains 1 IQ domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 ml

available

Delivery expected until 8/28/2025

Express Delivery: Save 7 days

Compare

Add to wishlist

Get an offer