ISG15

Item no.	20-203-421152
Manufacturer	GENWAY
Amount	0,1 ml
Category	Antibodies Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody
Applications	WB, ICC
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-27A1E0
Similar products	20-203-421152
Available
Genway ID:	GWB-27A1E0
Clone ID:	EPR3445
Immunogen:	A synthetic peptide corresponding to residues in human ISG15 was used as an immunogen.
Specificity:	A synthetic peptide corresponding to residues in human ISG15 was used as an immunogen.
Dilution:	WB: 1:2000 - 5000ICC: 1:100 - 250. ISG15 is a ubiquitin like protein that is covalently conjugated to cellular proteins after IFN-alpha/beta stimulation (2). ISG15 is conjugated to their targets by an enzymatic cascade involving an E1 activating enzyme an E2 conjugating enzyme and in some cases an E3 ligase. ISG15 conjugation plays an important role by impacting nuclear and cytoplasmic functions as well as in antiviral response because a human virus influenza B virus inhibits ISG15 conjugation. However the biological function of ISG15 modification remains unknown largely because only a few human ISG15 target proteins have been identified (3). 1. Manufactured under U. S. Patents No. 5 675 063 and 7 429 487

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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