BRG1

GWB-5CC73F

A synthetic peptide corresponding to residues near the C-terminus of human BRG1 protein was used as an immunogen.

WB: 1:1 000 - 10 000IHC: -. BRG1 protein (brahma-related gene 1) is a member of SWI/SNF family which mediates ATP-dependent chromatin remodeling processes. BRG is a central catalytic ATPase of the SWI/SNF chromatin-remodeling complex where it uses the energy derived from ATP-hydrolysis to disrupt the chromatin architecture of target promoters. Considered a major co-regulator of transcription BRG1 has been implicated in the activation and repression of gene expression through the modulation of chromatin in various tissues and physiological conditions. BRG1 appears to be a critical modulator of transcriptional regulation in cellular processes such as transcriptional regulation replication DNA repair and recombination (1 2). 1. Manufactured under U. S. Patents No. 5 675 063 and 7 429 487