RNA polymerase beta [8RB13]

GWB-DBFD55

IgG1

Reacts with beta subunit of RNA polymerase of E. coli

Nuclear Storage

WB: Use at a dilution of 1/1000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).

Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity).

Belongs to the RNA polymerase beta chain family.