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IgA [SPM187] (ready-to-use)

IgA [SPM187] (ready-to-use)

Item no.	20-272-191545
Manufacturer	GENWAY
Amount	7 ml
Category	Oncology Antibodies Immunohistochemistry Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	IHC
Clone	SPM187
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-27701C
Similar products	20-272-191545
Available
Genway ID:	GWB-27701C
Clone:	SPM187
Isotype:	IgG1Light chain: kappa
Immunogen:	Full length protein (Human).
Antigen Species:	Human
Positive Control:	Tonsil
Target:	IgA
Localization:	Secreted Storage
Buffer:	PBS pH 7. 4 containing 1%BSA and 0. 1% sodium azide
Application Note:	IHC-P: 1/1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer pH 6. 0 for 10 min followed by cooling at room temperature for 20 min. Not tested in other applications. Cellular
Localization:	Secreted
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 7 ml

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Delivery expected until 10/30/2025

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