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IgA [AD3]

IgA [AD3]

Item no.	20-272-192090
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Antibodies ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	ELISA
Clone	AD3
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-608DD9
Similar products	20-272-192090
Available
Genway ID:	GWB-608DD9
Clone:	AD3
Isotype:	IgG1
Immunogen:	Full length native protein (purified) (Human).
Antigen Species:	Human
Specificity:	This antibody reacts with alpha-chain of human IgA1 and IgA2. Specificity was confirmed by ELISA.
Target:	IgA
Concentration:	1 mg/ml
Purification Note:	Purified from ascites by DEAE chromatography and precipitation methods. Storage
Preservative:	15mM Sodium Azide; Constituents: 0. 2M Tris/HCl pH 7. 2
Application Note:	ELISA: Use at an assay dependant concentration. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/11/2025

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