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IgG Fab fragment [4A11]

IgG Fab fragment [4A11]

Item no.	20-272-192091
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	WB, ELISA
Clone	4A11
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-60D37C
Similar products	20-272-192091
Available
Genway ID:	GWB-60D37C
Clone:	4A11
Isotype:	IgG2b
Immunogen:	Purified human IgG
Antigen Species:	Human
Specificity:	Fab fragment of human IgG. Specificity was confirmed by Western blotting analysis of purified Fab fragment of human IgG under reducing conditions.
Target:	IgG Fab fragment
Concentration:	1 mg/ml
Purification Note:	More than 95% pure (by PAGE). Purified from ascites by DEAE chromatography. Storage
Buffer:	Phosphate-buffered saline pH 7. 4 containing 15mM sodium azide
Application Note:	For ELISA: Use at an assay dependent diluiton. For WB: Use at an assay dependent diluiton. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher
Subcellular Location:	Secreted.
Disease:	Chromosomal aberrations involving IGHG1 may be a cause of multiple myeloma [MIM:254500]. Translocation t(11; 14)(q13; q32) with CCND1; translocation t(4; 14)(p16. 3; q32. 3) with FGFR3; translocation t(6; 14)(p25; q32) with IRF4.
Miscellaneous:	Nie has the G1M(17) allotypic marker 97-K and the G1M(1) markers 239-D and 241-L. KOL and EU sequences have the G1M(3) marker and the G1M (non-1) markers.
Miscellaneous:	Nie also differs in the amidation states of 35 116 198 269 and 272.
Miscellaneous:	EU also differs in the amidation states of residues 155 166 177 195 198 269 and 272 and in the order of residues 268-272.
Miscellaneous:	KOL also differs in the amidation states of residues 198 267 and 272.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/11/2025

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