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alpha Tubulin [TU-01]

alpha Tubulin [TU-01]

Item no.	20-272-192713
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Antibodies Cell Biology Cytoskeleton Immunoprecipitation Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Mikrotubules By Organ Lung Cancer
Type	Antibody
Applications	WB, IF, IP, ICC, ELISA
Clone	TU-01
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-2E674F
Similar products	20-272-192713
Available
Genway ID:	GWB-2E674F
Clone:	TU-01
Isotype:	IgG1
Immunogen:	Fraction of tubulin purified from pig brain by two cycles of polymerization-depolymerization.
Antigen Species:	Pig
Target:	alpha Tubulin
Localization:	Major constituent of microtubules.
Concentration:	1 mg/ml
Purification Note:	Purified from ascites using precipitation methods. Storage
Buffer:	Phosphate buffered saline pH 7. 4 containing 15mM sodium azide
Application Note:	ELISA: Use at an assay dependant dilution. ICC: Use at a dilution of 1/100. For ICC we recommend not only fixing but also permeabilizing the cells. IF: Use at an assay dependant dilution. IP: Use at an assay dependant dilution. 20-272-192712 (TU-16)is better for IP application. WB: Use at an assay dependant dilution. Detects a band of approximately 55 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Major constituent of microtubules. Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis intracellular transport flagellar movement and in the cytoskeleton. Tubulin is a heterodimer which consists of alpha tubulin and beta tubulin.
Function:	Tubulin is the major constituent of microtubules. It binds two moles of GTP one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Subunit:	Dimer of alpha and beta chains.
Tissue Specificity:	Ubiquitously expressed although primarily in lung and brain.
Ptm:	Undergoes a tyrosination/detyrosination cycle the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL) respectively (By similarity).
Similarity:	Belongs to the tubulin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/11/2025

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