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Insulin &amp, Proinsulin [D3E7]

Insulin &amp, Proinsulin [D3E7]

Item no.	20-272-192855
Manufacturer	GENWAY
Amount	0.1 mg
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Immunohistochemistry ELISA Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody
Applications	IHC, ELISA
Clone	D3E7
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-D945B4
Similar products	20-272-192855
Available
Genway ID:	GWB-D945B4
Clone:	D3E7
Isotype:	IgG1Light chain: kappa
Immunogen:	Synthetic peptide ? Immunogen sequence information is commercially sensitive
Specificity:	Kd for this antibody is 6. 3 x 10-8M. This antibody is specific for both insulin and proinsulin
Target:	Insulin & Proinsulin
Localization:	Secreted
Concentration:	2 mg/ml Storage
Buffer:	Phosphate-buffered saline pH 7. 4 containing 0. 1% sodium azide
Application Note:	For a two-site enzyme immunoassay we recommend to use this antibody for labeling and for coating. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Cellular
Localization:	Secreted Detection of insulin and proinsulin. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides amino acids and fatty acids. It accelerates glycolysis the pentose phosphate cycle and glycogen synthesis in liver. Defects in insulin are the cause of familial hyperproinsulinemia.
Function:	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides amino acids and fatty acids. It accelerates glycolysis the pentose phosphate cycle and glycogen synthesis in liver.
Subunit:	Heterodimer of a B chain and an A chain linked by two disulfide bonds.
Subcellular Location:	Secreted.
Disease:	Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]. Pharmaceutical: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.
Similarity:	Belongs to the insulin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 11/13/2025

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