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Actin smooth muscle [HHF35] (sample)

Actin smooth muscle [HHF35] (sample)

Item no.	20-272-193806
Manufacturer	GENWAY
Amount	0.05 ml
Category	Oncology Antibodies Immunohistochemistry Primary Antibodies By Organ Skin Cancer
Type	Antibody
Applications	IHC
Clone	HHF35
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-8B26F9
Similar products	20-272-193806
Available
Genway ID:	GWB-8B26F9
Clone:	HHF35
Isotype:	IgG1
Immunogen:	Muscle actin purified from human myocardium
Antigen Species:	Human
Specificity:	Recognises muscle specific actin a 42kD protein specific for actin present in skeletal cardiac and smooth muscle. Clone HHF35 is specific for alpha actin and does not recognise beta actin. This antibody may be useful in the study of tumours arising from these muscle cells such as rhabdomyosarcomas leiomyomas and leiomyosarcomas.
Positive Control:	Skeletal tissue
Target:	Actin smooth muscle
Concentration:	tissue culture supernatant
Purification Note:	Hybridoma culture supernatant Storage
Buffer:	TCS containing PBS 1% BSA and 0. 09% sodium azide
Application Note:	For IHC-Fr: Use this product at 1:10-1:40. For IHC-P: Use this product at 1:10-1:40. This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Function:	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Subunit:	Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Subcellular Location:	Cytoplasm cytoskeleton.
Miscellaneous:	In vertebrates 3 main groups of actin isoforms alpha beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
Similarity:	Belongs to the actin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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