retinoic acid receptor gamma (RARG) mRNA

167C1a

This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Sterility: Filtered through a 0. 22 um membrane.

Forms a complex with PUS1 and the SRA1 RNA in the nucleus (By similarity).

Composed of three domains: a modulating N-terminal domain a DNA-binding domain and a C-terminal steroid-binding domain.

Contains 1 nuclear receptor DNA-binding domain. [1] Dey N. De P. K. Wang M. Zhang H. Dobrota E. A. Robertson K. A. and Durden D. L. CSK controls retinoic acid receptor (RAR) signaling: a RAR-c-SRC signaling axis is required for neuritogenic differentiation[2] Bour G. Plassat J. L. Bauer A. Lalevee S. and Rochette-Egly C. et al. Vinexin beta interacts with the non-phosphorylated AF-1 domain of retinoid receptor gamma (RARgamma) and represses RARgamma-mediated transcription[3] Hori Y. Gu X. Xie X. and Kim S. K. et al. Differentiation of insulin-producing cells from human neural progenitor cells[4] Yen A. Fenning R. Chandraratna R. Walker P. and Varvayanis S. et al. A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation retinoblastoma hypophosphorylation G0 arrest and cell differentiation[5] Andersson E. Rosdahl I. Torma H. and Vahlquist A. et al. Differential effects of UV irradiation on nuclear retinoid receptor levels in cultured keratinocytes and melanocytes[6] Krust A. Kastner P. Petkovich M. Zelent A. Chambon P. A third human retinoic acid receptor hRAR-gamma. [7] Ishikawa T. Umesono K. Mangelsdorf D. J. Aburatani H. Stanger B. Z. Shibasaki Y. Imawari M. Evans R. M. Takaku F. A functional retinoic acid receptor encoded by the gene on human chromosome 12. [8] Lehmann J. M. Hoffmann B. Pfahl M. Genomic organization of the retinoic acid receptor gamma gene. [9] Renaud J. -P. Rochel N. Ruff M. Vivat V. Chambon P. Gronemeyer H. Moras D. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. [10] Klaholz B. P. Renaud J. -P. Mitschler A. Zusi C. Chambon P. Gronemeyer H. Moras D. Conformational adaptation of agonists to the human nuclear receptor RAR gamma.