Lipase

Item no.	20-511-240760
Manufacturer	GENWAY
Amount	0,2 mg
Category	Antibodies Primary Antibodies
Type	Antibody
Clone	301
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-F5A9F9
Similar products	20-511-240760
Available
Genway ID:	GWB-F5A9F9
Isotype:	IgG1
Clone:	301Host Animal: Mouse
Immunogen:	Purified human pancreatic lipase
Specificity:	Specifically recognizes pancreatic lipase
Type of Product:	Monoclonal Antibodies to Enzymes
Concentration:	0. 9mg/ml (OD280nm)
Buffer:	PBS pH 7. 4Applications Notes : Suitable for use in ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. MAb to Lipase. Monoclonal Antibody to Lipase
Function:	The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). The enzyme functions in the presence of apolipoprotein C-2 on the luminal surface of vascular endothelium.
Catalytic Activity:	Triacylglycerol + H2O = diacylglycerol + a carboxylate.
Subunit:	Homodimer. Interacts with apolipoprotein C-2. Interacts with GPIHBP1.
Subcellular Location:	Cell membrane; Lipid-anchor GPI-anchor.
Disease:	Defects in LPL are a cause of familial chylomicronemia [MIM:238600]; also known as hyperlipoproteinemia type I. Familial chylomicronemia is a recessive disorder usually manifesting in childhood. On a normal diet patients often present with abdominal pain hepatosplenomegaly lipemia retinalis eruptive xanthomata and massive hypertriglyceridemia sometimes complicated with acute pancreatitis.
Disease:	Defects in LPL are the cause of lipoprotein lipase deficiency (LPL deficiency) [MIM:238600]. LPL deficiency leads to hypertriglyceridemia.
Similarity:	Belongs to the AB hydrolase superfamily. Lipase family.
Similarity:	Contains 1 PLAT domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0,2 mg

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Delivery expected until 11/13/2025

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