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Proinsulin

Proinsulin

Item no.	20-511-240972
Manufacturer	GENWAY
Amount	100units
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies ELISA Endocrine Regulation of Lipid Metabolism Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	ELISA
Clone	1G4 (Previou
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-D381B6
Similar products	20-511-240972
Available
Genway ID:	GWB-D381B6
Isotype:	IgG1. k
Clone:	1G4 (Previous OEM Concepts Clone #265-10174)Host Animal: Mouse. Hybridization of X63-Ag8-653 myeloma cells with spleen cells of a Balb/c mice
Specificity:	Does not cross-react with human bovine porcine insulin bovine and porcine proinsulin and human C-peptide
Immunogen:	Purified human proinsulin
Affinity Constant:	2. 6 x 10-7M
Type of Product:	Monoclonal Antibodies to Hormones and Steroids
Concentration:	4. 1 mg/ml (OD280nm E0. 1%=1. 4)Preservatives: NaN3
Buffer:	PBS. pH 7. 4Applications Notes : Detection of human proinsulin in two-site enzyme immunoassay. Can be used in immunohistochemistry on frozen sections. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Recommended pair for sandwich immunoassay: Capture: 20-511-240972; Detection: 20-511-240997 + 20-511-240971
Warning:	This product contains sodium azide which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing flush with copious volumes of water to prevent azide build-up in drains.
Buffer:	PBS pH 7. 4. Preservatives: 0. 1% Sodium azide MAb to Proinsulin. Monoclonal Antibody to Human Proinsulin
Function:	Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides amino acids and fatty acids. It accelerates glycolysis the pentose phosphate cycle and glycogen synthesis in liver.
Subunit:	Heterodimer of a B chain and an A chain linked by two disulfide bonds.
Subcellular Location:	Secreted.
Disease:	Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]. Pharmaceutical: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.
Similarity:	Belongs to the insulin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100units

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Delivery expected until 11/13/2025

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