Serum Amyloid A

IgG1

Human recombinant SAA. conjugated with carrier protein

Monoclonal Antibodies to Proteins and Bioactive Peptides

PBS. pH 7. 4Applications Notes : Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. . Recommended pairs for sandwich immunoassay:. Capture Detection. 20-511-242229 20-511-242224. 20-511-242213 20-511-242224. 20-511-242224 20-511-242229. 20-511-242283 20-511-242224

Major acute phase reactant. Apolipoprotein of the HDL complex.

Expressed by the liver; secreted in plasma.

This protein is the precursor of amyloid protein A which is formed by the removal of approximately 24 residues from the C-terminal end. Mass Spectrometry: Mass=11702; Mass_error=14; Method=MALDI; Range=19-122; Source=PubMed:12973732; . Mass Spectrometry: Mass=11682. 7; Method=MALDI; Range=19-122; Source=PubMed:12606051; . Mass Spectrometry: Mass=11526. 5; Method=MALDI; Range=20-122; Source=PubMed:12606051; . Mass Spectrometry: Mass=11439. 6; Method=MALDI; Range=21-122; Source=PubMed:12606051; . Mass Spectrometry: Mass=11363. 6; Method=MALDI; Range=20-121; Source=PubMed:12606051; . Mass Spectrometry: Mass=11235. 6; Method=MALDI; Range=20-120; Source=PubMed:12606051; . Mass Spectrometry: Mass=10872. 6; Method=MALDI; Range=22-119; Source=PubMed:12606051; .

Reactive secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.

JL is from a patient with ankylosing spondylitis.

Elevated serum SSA protein levels may be associated with lung cancer.