MOUSE ANTI PARAINFLUENZA VIRUS 3

PARAINFLUENZA VIRUS 3

Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

Specifically recognises an epitope within the haemagglutinin-neuraminidase (HN) protein of parainfluenza virus 3 (HPIV-3) an enveloped single-stranded RNA virus of the Paramyxoviridae family. Parainfluenza viruses are genetically and antigenically divided into the four types HPIV1-4 with HPIV-1 -2 and -3 being major causative agents of lower respiratory infections in the young and immunologically vulnerable. The HN protein of all HPIV is a 69-82kDa surface glycoprotein which mediates the attachment of the virus to the host cell through binding to cell surface sialic acid-containing receptors. The receptor-cleaving neuraminidase activity of HN is essential for further infection by HPIV by ensuring the release of progeny virions. Recommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGHuCAL Anti Mouse IgG2aRabbit Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMGoat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L) 1. Wang X. W. and Xu B. (1998) Stimulation of tumor-cell growth by alpha-fetoprotein. Int. J. Cancer 9:596-599. [1] \" Primary structures of human alpha-fetoprotein and its mRNA. \" Morinaga T. Sakai M. Wegmann T. G. Tamaoki T. Proc. Natl. Acad. Sci. U. S. A. 80:4604-4608(1983) [PubMed: 6192439] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] \" Structure polymorphism and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene. \" Gibbs P. E. M. Zielinski R. Boyd C. Dugaiczyk A. Biochemistry 26:1332-1343(1987) [PubMed: 2436661] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [3] \" Complete sequencing and characterization of 21 243 full-length human cDNAs. \" Ota T. Suzuki Y. Nishikawa T. Otsuki T. Sugiyama T. Irie R. Wakamatsu A. Hayashi K. Sato H. Nagai K. Kimura K. Makita H. Sekine M. Obayashi M. Nishi T. Shibahara T. Tanaka T. Ishii S. Yamamoto J. Saito K. Kawai Y. Isono Y. Nakamura Y. Nagahari K. Murakami K. Yasuda T. Iwayanagi T. Wagatsuma M. Shiratori A. Sudo H. Hosoiri T. Kaku Y. Kodaira H. Kondo H. Sugawara M. Takahashi M. Kanda K. Yokoi T. Furuya T. Kikkawa E. Omura Y. Abe K. Kamihara K. Katsuta N. Sato K. Tanikawa M. Yamazaki M. Ninomiya K. Ishibashi T. Yamashita H. Murakawa K. Fujimori K. Tanai H. Kimata M. Watanabe M. Hiraoka S. Chiba Y. Ishida S. Ono Y. Takiguchi S. Watanabe S. Yosida M. Hotuta T. Kusano J. Kanehori K. Takahashi-Fujii A. Hara H. Tanase T. -O. Nomura Y. Togiya S. Komai F. Hara R. Takeuchi K. Arita M. Imose N. Musashino K. Yuuki H. Oshima A. Sasaki N. Aotsuka S. Yoshikawa Y. Matsunawa H. Ichihara T. Shiohata N. Sano S. Moriya S. Momiyama H. Satoh N. Takami S. Terashima Y. Suzuki O. Nakagawa S. Senoh A. Mizoguchi H. Goto Y. Shimizu F. Wakebe H. Hishigaki H. Watanabe T. Sugiyama A. Takemoto M. Kawakami B. Yamazaki M. Watanabe K. Kumagai A. Itakura S. Fukuzumi Y. Fujimori Y. Komiyama M. Tashiro H. Tanigami A. Fujiwara T. Ono T. Yamada K. Fujii Y. Ozaki K. Hirao M. Ohmori Y. Kawabata A. Hikiji T. Kobatake N. Inagaki H. Ikema Y. Okamoto S. Okitani R. Kawakami T. Noguchi S. Itoh T. Shigeta K. Senba T. Matsumura K. Nakajima Y. Mizuno T. Morinaga M. Sasaki M. Togashi T. Oyama M. Hata H. Watanabe M. Komatsu T. Mizushima-Sugano J. Satoh T. Shirai Y. Takahashi Y. Nakagawa K. Okumura K. Nagase T. Nomura N. Kikuchi H. Masuho Y. Yamashita R. Nakai K. Yada T. Nakamura Y. Ohara O. Isogai T. Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] VARIANT GLY-570. Tissue: Heart. [4] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung. [5] \" A G--> A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP). \" McVey J. H. Michaelides K. Hansen L. P. Ferguson-Smith M. Tilghman S. Krumlauf R. Tuddenham E. G. D. Hum. Mol. Genet. 2:379-384(1993) [PubMed: 7684942] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28. [6] Lubec G. Vishwanath V. Submitted (MAR-2007) to UniProtKBCited for: PROTEIN SEQUENCE OF 311-332; 348-372 AND 422-437 MASS SPECTROMETRY. Tissue: Brain and Cajal-Retzius cell. [7] \" Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA. \" Beattie W. G. Dugaiczyk A. Gene 20:415-422(1982) [PubMed: 6187626] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 429-556. [8] \" Human alpha-fetoprotein primary structure: a mass spectrometric study. \" Pucci P. Siciliano R. Malorni A. Marino G. Tecce M. F. Ceccarini C. Terrana B. Biochemistry 30:5061-5066(1991) [PubMed: 1709810] [Abstract]Cited for: PARTIAL PROTEIN SEQUENCE OF 19-609. [9] \" Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis. \" Yachnin S. Hsu R. Heinrikson R. L. Miller J. B. Biochim. Biophys. Acta 493:418-428(1977) [PubMed: 70228] [Abstract]Cited for: PRELIMINARY PROTEIN SEQUENCE OF 19-35. [10] \" Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma. \" Aoyagi Y. Ikenaka T. Ichida F. Cancer Res. 37:3663-3667(1977) [PubMed: 71198] [Abstract]Cited for: PRELIMINARY PROTEIN SEQUENCE OF 19-38.