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UBIQUITIN

UBIQUITIN


Item no.	20-783-70448
Manufacturer	GENWAY
Amount	0.02 mg
Category	Oncology Antibodies Cell Biology Cell Status Flow Cytometry Immunohistochemistry Autophagy Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	FC, IHC
Clone	1B4-UB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-C0A4D0
Similar products	20-783-70448
Available
Genway ID:	GWB-C0A4D0
Specificity:	UBIQUITIN
Specificity:	UBIQUITIN
Clone:	1B4-UB
Immunogen:	Ubiquitin from bovine erythrocytes conjugated to bovine gamma globulin
Fusion Partner:	Spleen cells from immunised BALB/c mouse were fused with cells of the mouse PAI myeloma cell line.
Specificity Note:	This product recognises both human and bovine ubiquitin.
Immunohistology:	This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Histology: Human hypophysis
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Flow Cytometry:	Membrane permeabilisation is required for this method. We recommend the use of Leucoperm for this purpose. Suggested
Dilution:	Flow Cytometry - 1/10 - 1/50Immunohistology - Frozen - 1/500 - 1/1000
Function:	Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions including maintenance of chromatin structure regulation of gene expression stress response ribosome biogenesis and DNA repair.
Subcellular Location:	Cytoplasm. Nucleus.
Ptm:	Several types of polymeric chains can be formed depending on the lysine used for the assembly.
Miscellaneous:	Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail repeats the number of repeats differ between species and strains. In some species there is a final amino-acid after the last repeat here in human a Val. Some ubiquitin genes contain a single copy of ubiquitin fused to a ribosomal protein (either L40 or S27a).
Similarity:	Belongs to the ubiquitin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.02 mg

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Delivery expected until 11/13/2025

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