Comparison

KIR

Item no. 20-783-71754
Manufacturer GENWAY
Amount 0.1 mg
Category
Type Antibody
Applications FC
Clone NKVFS1
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-3C5FB4
Similar products 20-783-71754
Available
Genway ID:
GWB-3C5FB4
Specificity:
KIRNCBI
Gene ID:
3802
Specificity:
KIR
Clone:
NKVFS1
Specificity Note:
This product recognises KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family CD158a CD158b and P50. 3. KIR2D family members are cell surface glycoproteins with two Ig domains which are expressed on natural killer cells and some T cells. Clone NKVFS1 specifically recognises the long and short forms CD158a and CD158b (KIR2DL KIR2DS1 and KIR2DS2 respectively) and also p50. 3 (KIR2DS4). The clone is reported to have functional activity activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms. We recommend the use of for this purpose.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09%Sodium Azide1%Bovine Serum AlbuminSuggested
Flow Cytometry:
Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:
Flow Cytometry - Neat - 1/10 1. Spaggiari. G. M. et al. (2002) Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: evidence for a negative regulation exerted by members of the inhibitory receptor superfamily. 2. Spaggiari. G. M. et al. (2002) Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mg
Available: In stock
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