CD49b


Item no.	20-783-72476
Manufacturer	GENWAY
Amount	0.2 mg
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies Flow Cytometry Immunohistochemistry Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	FC, IHC
Clone	AK7
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-113F1C
Similar products	20-783-72476
Available
Genway ID:	GWB-113F1C
Specificity:	CD49bNCBI
Gene ID:	3673
Specificity:	CD49b
Clone:	AK7
Fusion Partner:	Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity Note:	This product recognises the integrin alpha 2 subunit which is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets long term cultivated T cells approximately 50% of monocytes and most adherent cell lines. This product inhibits cell attachment to collagen. Histology: Tonsil
Preparation:	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Flow Cytometry:	Use 10ul of the suggested working dilution to label 106 cells in 100ul. Suggested
Dilution:	Flow Cytometry - 1/50 - 1/100Immunohistology - Frozen - 1/500 - 1/1000 1. Favaloro. E. J. et al. (1990) Co-expression of haemopoietic antigens on vascular endothelial cells: a detailed phenotypic analysis. 2. Mazurov. A. V. et al. (1991) A monoclonal antibody. VM64. reacts with a 130 kDa glycoprotein common to platelets and endothelial cells: heterogeneity in antibody binding to human aortic endothelial cells. 3. Yoshino. N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts. cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. 4. Cialet. M. et al. (2002) VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 9/11/2025

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