IL-6


Item no.	20-783-72824
Manufacturer	GENWAY
Amount	0.5 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Carcinoma Hematology Leukemia Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Applications	ELISA
Clone	MQ2-39C3
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-D92A79
Similar products	20-783-72824
Available
Genway ID:	GWB-D92A79
Specificity:	IL-6
Specificity:	IL-6
Clone:	MQ2-39C3
Specificity Note:	This product recognises human interleukin 6.
Buffer Solution:	Borate buffered saline
Preservative Stabilisers:		None present
Function:	IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells it induces myeloma and plasmacytoma growth it induces nerve cells differentiation in hepatocytes it induces acute phase reactants.
Subcellular Location:	Secreted.
Ptm:	N- and O-glycosylated.
Polymorphism:	Genetic variations in IL6 may be correlated with bone mineral density (BMD). Low BMD is a risk factor for osteoporotic fracture. Osteoporosis is characterized by reduced bone mineral density disrutption of bone microarchitecture and the alteration of the amount and variety of non-collagenous proteins in bone. Osteoporotic bones are more at risk of fracture.
Disease:	Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe debilitating extraarticular features and occasionally fatal complications. Despite medical treatment many children still experience early joint destruction necessitating surgical replacement.
Disease:	At least 1 polymorphism in the IL6 gene renders HIV-infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS.
Similarity:	Belongs to the IL-6 superfamily.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 11/13/2025

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