IgA1


Item no.	20-783-73367
Manufacturer	GENWAY
Amount	0.5 mg
Category	Oncology Antibodies ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	ELISA
Clone	14A/3C10
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-504780
Similar products	20-783-73367
Available
Genway ID:	GWB-504780
Specificity:	IgA1
Specificity:	IgA1
Clone:	14A/3C10
Immunogen:	Purified human IgA from colostrum
Specificity Note:	This product is specific for Human IgA1 Fc-region. Minimal reactivity is seen with IgA2 IgG and IgM as determined by ELISA.
Preparation:	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5 mg

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Delivery expected until 9/11/2025

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