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Na+/H+ EXCHANGER-1

Na+/H+ EXCHANGER-1


Item no.	20-783-74683
Manufacturer	GENWAY
Amount	0.1 mg
Category	Antibodies Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody
Clone	4000000000
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-EB9CC9
Similar products	20-783-74683
Available
Genway ID:	GWB-EB9CC9
Specificity:	Na+/H+ EXCHANGER-1
Specificity:	Na+/H+ EXCHANGER-1
Clone:	4000000000
Immunogen:	Maltose binding protein fusion protein containing the entire C-terminal hydrophilic domain of porcine NHE1
Specificity Note:	This product is specific for the Na+/H+ exchanger-1 NHE1.
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium Azide (NaN3)
Function:	Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. Biophysicochemical Properties:
Subunit:	Interacts with tescalcin CHP and CHP2.
Subcellular Location:	Membrane; Multi-pass membrane protein.
Tissue Specificity:	Kidney and intestine.
Ptm:	Phosphorylated upon DNA damage probably by ATM or ATR.
Ptm:	O-glycosylated.
Miscellaneous:	Inhibited by amiloride and 5-amino-substituted derivatives and activated in a cooperative fashion by intracellular H(+). In quiescent cells upon growth factor stimulation the apparent affinity for internal H(+) is increased resulting in a persistent rise in cytoplasmic pH.
Similarity:	Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2. A. 36) family [view classification]. 1. Rutherford. P. A. et al. (1997) Expression of Na(+)-H+ exchanger isoforms NHE1 and NHE3 in kidney and

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/11/2025

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