Calretinin

Rabbit IgG

Mesothelioma

Recombinant full length mouse calretinin protein. Recognizes a protein of 31. 5kDa identified as Calretinin. Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural mitif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas.