ROC1

Item no.	20-786-255491
Manufacturer	GENWAY
Amount	7 ml
Category	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Primary Antibodies
Type	Antibody
Applications	IHC
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-9A55BF
Similar products	20-786-255491
Available
Genway ID:	GWB-9A55BF
Isotype:	Rabbit IgG
Positive Control:	Hela cells. Tonsil
Staining Pattern:	Nuclear
Immunogen:	A synthetic peptide derived from the C-terminus of human ROC1. ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11 a subunit of the anaphase-promoting complex (APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2 a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1-and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 7 ml

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Delivery expected until 11/13/2025

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