IgA


Item no.	25-783-76055
Manufacturer	GENWAY
Amount	1 mg
Category	Oncology Antibodies Flow Cytometry Immunohistochemistry Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	FC, IHC
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-3A656A
Similar products	25-783-76055
Available
Genway ID:	GWB-3A656A
Specificity:	IgA
Specificity:	IgA
Immunogen:	Purified equine IgA
Specificity Note:	This product recognises equine IgA and shows no cross - reactivity with other equine immunoglobulin classes in immunoelectrophoresis.
Antiserum Preparation:	Antisera to equine IgA were raised by repeated immunisation of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution:	Phosphate buffered saline
Preservative Stabilisers:		0. 09%Sodium Azide0. 2%Bovine Serum AlbuminSuggested
Dilution:	Suggested
Dilution:	Flow Cytometry - 1/20 - 1/100Immunohistology - Frozen - 1/20 - 1/100
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 10/30/2025

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