IgG


Item no.	25-783-76887
Manufacturer	GENWAY
Amount	1 mg
Category	Oncology Antibodies Immunohistochemistry ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Type	Antibody
Applications	IHC, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-4D785D
Similar products	25-783-76887
Available
Genway ID:	GWB-4D785D
Specificity:	IgGNCBI
Gene ID:	16017
Specificity:	IgG
Specificity Note:	Mouse IgG (all subclasses). Cross reactivity with rat IgG is expected. Cross reactivity with human serum proteins has been minimised by solid phase adsorbtion. This product is suitable as a bridge in a PAP / APAAP complex. Peroxidase anti-Peroxidase (PAP) complexes are formed by antibodies raised towards Horse Radish Peroxidase (HRP) binding to HRP molecules. Such complexes are used as signal amplification reagents in immunochemical staining techniques. It must be emphasised that the primary antibody must be raised in the same species as the antibodies used to form the PAP complex so that a secondary \" linker\" antibody can be used to \" bridge\" the primary antibody to the PAP complex.
Preparation:	Purified IgG was prepared from whole serum by affinity chromatography. F(ab\' )2 fragments were prepared by pepsin digestion of the IgG followed by a gel filtration step to remove any remaining intact IgG or Fc fragments.
Buffer Solution:	Phosphate buffered saline pH7. 2
Preservative Stabilisers:		0. 09%Sodium AzideSuggested
Dilution:	Suggested
Dilution:	Immunohistology - Frozen - 1/100 - 1/500Immunohistology - Paraffin - 1/100 - 1/500ELISA - 1/500 - 1/1000
Subcellular Location:	Secreted.
Disease:	Chromosomal aberrations involving IGHG1 may be a cause of multiple myeloma [MIM:254500]. Translocation t(11; 14)(q13; q32) with CCND1; translocation t(4; 14)(p16. 3; q32. 3) with FGFR3; translocation t(6; 14)(p25; q32) with IRF4.
Miscellaneous:	Nie has the G1M(17) allotypic marker 97-K and the G1M(1) markers 239-D and 241-L. KOL and EU sequences have the G1M(3) marker and the G1M (non-1) markers.
Miscellaneous:	Nie also differs in the amidation states of 35 116 198 269 and 272.
Miscellaneous:	EU also differs in the amidation states of residues 155 166 177 195 198 269 and 272 and in the order of residues 268-272.
Miscellaneous:	KOL also differs in the amidation states of residues 198 267 and 272.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 9/11/2025

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