Manufacturer GENWAY
Type Antibody
Specific against Rat
Applications IP
Amount 0.1 mg
Host Mouse
ArtNr 20-783-314576
Genway ID:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution:
Phosphate buffered saline
Preservative Stabilisers:
0. 09% Sodium AzideApprox. Protein Concentrations: IgG concentration 1. 0mg/ml
Membrane fraction of thioglycollate-elicited rat peripheral cells.
Recognises the rat CD200 (OX2) receptor 1. This antigen is a heavily glycosylated 60-100kD cell surface molecule expressed by cells of the myeloid lineage but not by T or B lymphocytes. This antibody has been shown to block the interaction of CD200 receptor 1 with CD200. Clone OX-102 has been reported to work in western blotting applications. Recommended Negative Controls: MOUSE IgG1 NEGATIVE CONTROLRecommended Secondary Antibodies: Rabbit Anti Mouse IgGGoat Anti Mouse IgGGoat Anti Mouse IgG (H/L)Goat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgG1Goat Anti Mouse IgG (Fc)Sheep Anti Mouse IgG (H/L)
Receptor for the CD200/OX2 cell surface glycoprotein. Subcellular locationCell membrane; Single-pass type I membrane protein. Tissue specificityRestricted to cells of the myeloid lineage. Ref. 1Post-translational modificationPhosphorylated on tyrosine residues. Highly N-glycosylated. Sequence similaritiesBelongs to the CD200R family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. [1] \" CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with Bcl10 and activate NF-kappaB. \" Bertin J. Wang L. Guo Y. Jacobson M. D. Poyet J. -L. Srinivasula S. M. Merriam S. DiStefano P. S. Alnemri E. S. J. Biol. Chem. 276:11877-11882(2001) [PubMed: 11278692] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] \" The DNA sequence of human chromosome 7. \" Hillier L. W. Fulton R. S. Fulton L. A. Graves T. A. Pepin K. H. Wagner-McPherson C. Layman D. Maas J. Jaeger S. Walker R. Wylie K. Sekhon M. Becker M. C. O\' Laughlin M. D. Schaller M. E. Fewell G. A. Delehaunty K. D. Miner T. L. Nash W. E. Cordes M. Du H. Sun H. Edwards J. Bradshaw-Cordum H. Ali J. Andrews S. Isak A. Vanbrunt A. Nguyen C. Du F. Lamar B. Courtney L. Kalicki J. Ozersky P. Bielicki L. Scott K. Holmes A. Harkins R. Harris A. Strong C. M. Hou S. Tomlinson C. Dauphin-Kohlberg S. Kozlowicz-Reilly A. Leonard S. Rohlfing T. Rock S. M. Tin-Wollam A. -M. Abbott A. Minx P. Maupin R. Strowmatt C. Latreille P. Miller N. Johnson D. Murray J. Woessner J. P. Wendl M. C. Yang S. -P. Schultz B. R. Wallis J. W. Spieth J. Bieri T. A. Nelson J. O. Berkowicz N. Wohldmann P. E. Cook L. L. Hickenbotham M. T. Eldred J. Williams D. Bedell J. A. Mardis E. R. Clifton S. W. Chissoe S. L. Marra M. A. Raymond C. Haugen E. Gillett W. Zhou Y. James R. Phelps K. Iadanoto S. Bubb K. Simms E. Levy R. Clendenning J. Kaul R. Kent W. J. Furey T. S. Baertsch R. A. Brent M. R. Keibler E. Flicek P. Bork P. Suyama M. Bailey J. A. Portnoy M. E. Torrents D. Chinwalla A. T. Gish W. R. Eddy S. R. McPherson J. D. Olson M. V. Eichler E. E. Green E. D. Waterston R. H. Wilson R. K. Nature 424:157-164(2003) [PubMed: 12853948] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [3] \" Human chromosome 7: DNA sequence and biology. \" Scherer S. W. Cheung J. MacDonald J. R. Osborne L. R. Nakabayashi K. Herbrick J. -A. Carson A. R. Parker-Katiraee L. Skaug J. Khaja R. Zhang J. Hudek A. K. Li M. Haddad M. Duggan G. E. Fernandez B. A. Kanematsu E. Gentles S. Christopoulos C. C. Choufani S. Kwasnicka D. Zheng X. H. Lai Z. Nusskern D. R. Zhang Q. Gu Z. Lu F. Zeesman S. Nowaczyk M. J. Teshima I. Chitayat D. Shuman C. Weksberg R. Zackai E. H. Grebe T. A. Cox S. R. Kirkpatrick S. J. Rahman N. Friedman J. M. Heng H. H. Q. Pelicci P. G. Lo-Coco F. Belloni E. Shaffer L. G. Pober B. Morton C. C. Gusella J. F. Bruns G. A. P. Korf B. R. Quade B. J. Ligon A. H. Ferguson H. Higgins A. W. Leach N. T. Herrick S. R. Lemyre E. Farra C. G. Kim H. -G. Summers A. M. Gripp K. W. Roberts W. Szatmari P. Winsor E. J. T. Grzeschik K. -H. Teebi A. Minassian B. A. Kere J. Armengol L. Pujana M. A. Estivill X. Wilson M. D. Koop B. F. Tosi S. Moore G. E. Boright A. P. Zlotorynski E. Kerem B. Kroisel P. M. Petek E. Oscier D. G. Mould S. J. Doehner H. Doehner K. Rommens J. M. Vincent J. B. Venter J. C. Li P. W. Mural R. J. Adams M. D. Tsui L. -C. Science 300:767-772(2003) [PubMed: 12690205] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [4] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. [5] \" Carma1 a CARD-containing binding partner of Bcl10 induces Bcl10 phosphorylation and NF-kappaB activation. \" Gaide O. Martinon F. Micheau O. Bonnet D. Thome M. Tschopp J. FEBS Lett. 496:121-127(2001) [PubMed: 11356195] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-1154. [6] ErratumGaide O. Martinon F. Micheau O. Bonnet D. Thome M. Tschopp J. FEBS Lett. 505:198-198(2001) [7] \" Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1. \" Ohnuma K. Uchiyama M. Yamochi T. Nishibashi K. Hosono O. Takahashi N. Kina S. Tanaka H. Lin X. Dang N. H. Morimoto C. J. Biol. Chem. 282:10117-10131(2007) [PubMed: 17287217] [Abstract]Cited for: IDENTIFICATION IN A MEMBRANE RAFT COMPLEX INTERACTION WITH DPP4 SUBCELLULAR LOCATION IDENTIFICATION BY MASS SPECTROMETRY. [8] Colinge J. Superti-Furga G. Bennett K. L. Submitted (OCT-2008) to UniProtKBCited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. [9] \" Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. \" Mayya V. Lundgren D. H. Hwang S. -I. Rezaul K. Wu L. Eng J. K. Rodionov V. Han D. K. Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract]Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-466; SER-593 AND SER-925 MASS SPECTROMETRY. Tissue: Leukemic T-cell.
Amount: 0.1 mg
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