« Back
Home /
CDC2 (Phospho-Thr161) Antibody Blocking Peptide

CDC2 (Phospho-Thr161) Antibody Blocking Peptide

Item no.	06-785-213119
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Peptides & Proteins Peptides By Organ Lung Cancer
Type	Peptides
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GWB-F86CCB
Similar products	06-785-213119
Available
Genway ID:	GWB-F86CCB
Function:	Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Catalytic Activity:	ATP + a protein = ADP + a phosphoprotein.
Catalytic Activity:	ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Enzyme Regulation:	Phosphorylation at Thr-14 or Tyr-15 inactivates the enzyme while phosphorylation at Thr-161 activates it.
Subunit:	Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLGAP5. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.
Subcellular Location:	Nucleus (By similarity).
Similarity:	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Similarity:	Contains 1 protein kinase domain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg

available

Delivery expected until 11/13/2025

Express Delivery: Save 9 days

Compare

Add to wishlist

Get an offer