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SNRPA (small nuclear ribonucleoprotein polypeptide A)

SNRPA (small nuclear ribonucleoprotein polypeptide A)

Item no.	18-003-43598
Manufacturer	GENWAY
Amount	0.05 mg
Category	Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Immunohistochemistry Western Blot Peptides
Type	Peptides
Applications	WB, IHC
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GWB-4BDA85
Similar products	18-003-43598
Available
Genway ID:	GWB-4BDA85
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human SNRPA. Western Blot: Suggested dilution at 0. 5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50. 000 - 100. 000 as second antibody.
ELISA Titre:	1:312500
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. SNRPA binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Function:	Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Subunit:	Belongs to the spliceosome where it is associated with snRNP U1. Interacts with SFPQ. Also component of a snRNP-free complex with SFPQ.
Subcellular Location:	Nucleus.
Similarity:	Belongs to the RRM U1 A/B\' \' family.
Similarity:	Contains 2 RRM (RNA recognition motif) domains. Shajani. Z. (2005) J. Mol. Biol. 349 (4). 699-715.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 9/11/2025

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