Comparison

Neuropeptide Y receptor type 4

Item no. 18-461-10323
Manufacturer GENWAY
Amount 0.05 ml
Category
Type Peptides
Applications IHC
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GWB-C5F09D
Similar products 18-461-10323
Available
Genway ID:
GWB-C5F09D
Immunogen:
3rd cytoplasmic domain of human. Synthetic peptide - KLH conjugated.
Uses: IHC (16 ug/ml) (Optimal dilution to be determined by the researcher)
Function:
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP PP (2-36) and [Ile-31 Gln-34] PP & gt; [Pro-34] PYY & gt; PYY and [Leu-31 Pro-34] NPY & gt; NPY & gt; PYY (3-36) and NPY (2-36) & gt; PP (13-36) & gt; PP (31-36) & gt; NPY free acid.
Subcellular Location:
Membrane; multi-pass membrane protein.
Tissue Specificity:
Highest levels found in brain coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine.
Similarity:
Belongs to the G-protein coupled receptor 1 family [view classification]. [1] Brichese L. Cazettes G. and Valette A. et al. JNK is associated with Bcl-2 and PP1 in mitochondria: paclitaxel induces its activation and its association with the phosphorylated form of Bcl-2[2] Terry-Lorenzo R. T. Elliot E. Weiser D. C. Prickett T. D. Brautigan D. L. and Shenolikar S. Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton[3] Tanji C. Yamamoto H. Yorioka N. Kohno N. Kikuchi K. and Kikuchi A. A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta) and mediates protein kinase A-dependent inhibition of GSK-3beta[4] Wu D. Y. Tkachuck D. C. Roberson R. S. and Schubach W. H. et al. The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity[5] Benaim G. and Villalobo A. et al. Phosphorylation of calmodulin. Functional implications[6] Bard J. A. Walker M. W. Branchek T. A. Weinshank R. L. Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide neuropeptide Y and peptide YY. [7] Lundell I. Blomqvist A. G. Berglund M. M. Schober D. A. Johnson D. Statnick M. A. Gadski R. A. Gehlert D. R. Larhammar D. Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY. [8] Yan H. Yang J. Marasco J. Yamaguchi K. Brenner S. Collins F. Karbon W. Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors. [9] Kopatz S. A. Aronstam R. S. Sharma S. V. cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www. cdna. org).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.05 ml
Available: In stock
available

Delivery expected until 10/30/2025 

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close