Neuropeptide FF receptor 2

Synthetic peptide - KLH conjugated.
Uses: IHC (Optimal dilution to be determined by the researcher)

Membrane; multi-pass membrane protein.

Belongs to the G-protein coupled receptor 1 family [view classification]. [1] Anko M. L. and Panula P. et al. Regulation of endogenous human NPFF2 receptor by neuropeptide FF in SK-N-MC neuroblastoma cell line[2] Mollereau C. Mazarguil H. Zajac J. M. and Roumy M. et al. Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells[3] Engstrom M. Wurster S. Savola J. M. and Panula P. et al. Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors[4] Laemmle B. Schindler M. Beilmann M. Hamilton B. S. Doods H. N. and Wieland H. A. Characterization of the NPGP receptor and identification of a novel short mRNA isoform in human hypothalamus[5] Bonini J. A. Jones K. A. Adham N. Forray C. Artymyshyn R. Durkin M. M. Smith K. E. Tamm J. A. Boteju L. W. Lakhlani P. P. et al. Identification and characterization of two G protein-coupled receptors for neuropeptide FF[6] Cikos S. Gregor P. Koppel J. Sequence and tissue distribution of a novel G-protein-coupled receptor expressed prominently in human placenta. [7] Elshourbagy N. A. Ames R. S. L. R. Foley J. J. Chambers J. K. Szekeres P. G. Evans N. A. Schmidt D. B. Buckley P. T. Dytko G. M. et al. Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. [8] Bonini J. A. Jones K. A. Adham N. Forray C. Artymyshyn R. Durkin M. M. Smith K. E. Tamm J. A. Boteju L. W. Lakhlani P. P. et al. Identification and characterization of two G protein-coupled receptors for neuropeptide FF. [9] Parker R. M. C. Copeland N. G. Eyre H. J. Liu M. Gilbert D. J. Crawford J. Couzens M. Sutherland G. R. Jenkins N. A. Herzog H. et al. Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. [10] Liu Q. Guan X. -M. McDonald T. P. Jiang Q. Zeng Z. Marlene J. Williams D. L. Jr. Hong Y. Figueroa D. Clements M. K. et al. Identification and characterization of two cognate receptors for mammalian FMRFamide-like neuropeptides.