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Human TBG

Human TBG

Item no.	11-511-248590
Manufacturer	GENWAY
Amount	5mg
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Thyroid Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GWB-8DBE92
Similar products	11-511-248590
Available
Genway ID:	GWB-8DBE92
Specificity:	Thyroxine Binding Globulin (TBG)
Type of Product:	Purified Hormones and SteroidsPreservatives: 0. 05% sodium azide
Buffer:	10mM PBS pH 7. 4Applications Notes : Specific methodologies have not been tested using this product.
Warning:	This product contains sodium azide. which has been classified as Xn (Harmful). in European Directive 67/548/EEC in the concentration range of 0. 1â ??1. 0%. When disposing of this reagent through lead or copper plumbing. flush with copious volumes of water to prevent azide build-up in drains.
Concentration:	Concentration is lot specific Human TBG. Human Thyroxine Binding Globulin (TBG) Antigen. Molecular weight 60kDa (chromatographic and electrophoretic methods)
Function:	Major thyroid hormone transport protein in serum.
Subcellular Location:	Secreted.
Tissue Specificity:	Expressed by the liver and secreted in plasma.
Polymorphism:	Two qualitative TBG variants occur in particular populations. TBG-A is found in 40% of Australian aborigines it has reduced affinity for thyroxine and triiodothyroxine and increased susceptibility to inactivation by heat or acid. TBG-S (\' s\' for slow shift on isoelectic focusing) is found in blacks Eskimos Melanesians Polynesians and Indonesians but not in Caucasians; TBG-S is slightly more thermolabile.
Disease:	Defects in SERPINA7 are a cause of TBG deficiency [MIM:314200]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies characterized by either reduced or increased TBG levels in the serum. Patients show respectively reduced or elevated protein-bound iodine but are euthyroid.
Similarity:	Belongs to the serpin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 11/13/2025

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