NATIVE HUMAN IgA

GWB-3FA04A

Precipitation and gel filtration

The sequence of the A2m1 allotype is shown. Sequence similaritiesContains 3 Ig-like (immunoglobulin-like) domains. Caution: N-glycosylation was reported in milk on the non-canonical Asn-92 site (Ref. 9). However according to Ref. 10 N-glycosylation from the same tissue was found to be absent at this site. Sequence cautionThe sequence AAB59396. 1 differs from that shown. Reason: Erroneous initiation. 1. Kruchten A. et al. (2006) Dynamin as a mover and pincher during cell migration and invasion. J. Cell. Sci. 119:1683-90. 2. Ferguson S. et al. (2007) A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science. 316:570-4. [1] \" Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. \" Obar R. A. Collins C. A. Hammarback J. A. Shpetner H. S. Vallee R. B. Nature 347:256-261(1990) [PubMed: 2144893] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Strain: Sprague-Dawley. Tissue: Brain. [2] Lubec G. Afjehi-Sadat L. Diao W. Submitted (APR-2007) to UniProtKBCited for: PROTEIN SEQUENCE OF 5-15; 45-54; 67-87; 91-107; 116-157; 167-188; 257-266; 300-315; 328-342; 400-415; 511-522 AND 584-594 (ISOFORM 1/2/3/4) MASS SPECTROMETRY. Strain: Sprague-Dawley. Tissue: Hippocampus and Spinal cord. [3] \" The in vivo phosphorylation sites of rat brain dynamin I. \" Graham M. E. Anggono V. Bache N. Larsen M. R. Craft G. E. Robinson P. J. J. Biol. Chem. 282:14695-14707(2007) [PubMed: 17376771] [Abstract]Cited for: PROTEIN SEQUENCE OF 343-364; 511-522 AND 797-838 (ISOFORM 1/2/4/5/6/8) PROTEIN SEQUENCE OF 847-864 (ISOFORM 1/5) PHOSPHORYLATION AT SER-347; SER-512; SER-774; SER-778; SER-822; SER-851 AND SER-857 MASS SPECTROMETRY. [4] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 368-581 (ISOFORM 5/6/7/8). Tissue: Brain. [5] \" Amgen rat EST program. \" Amgen EST programSubmitted (APR-2003) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 668-864 (ISOFORM 1/5). Tissue: Brain and Hypothalamus. [6] \" The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. \" Ringstad N. Nemoto Y. De Camilli P. Proc. Natl. Acad. Sci. U. S. A. 94:8569-8574(1997) [PubMed: 9238017] [Abstract]Cited for: INTERACTION WITH SH3GL1; SH3GL2 AND SH3GL3. Tissue: Brain. [7] \" Differential distribution of dynamin isoforms in mammalian cells. \" Cao H. Garcia F. McNiven M. A. Mol. Biol. Cell 9:2595-2609(1998) [PubMed: 9725914] [Abstract]Cited for: ALTERNATIVE SPLICING SUBCELLULAR LOCATION TISSUE SPECIFICITY. [8] \" The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis. \" Cousin M. A. Robinson P. J. Trends Neurosci. 24:659-665(2001) [PubMed: 11672811] [Abstract]Cited for: ROLE OF PHOSPHORYLATION. [9] \" Cdk5 is essential for synaptic vesicle endocytosis. \" Tan T. C. Valova V. A. Malladi C. S. Graham M. E. Berven L. A. Jupp O. J. Hansra G. McClure S. J. Sarcevic B. Boadle R. A. Larsen M. R. Cousin M. A. Robinson P. J. Nat. Cell Biol. 5:701-710(2003) [PubMed: 12855954] [Abstract]Cited for: PHOSPHORYLATION BY CDK5. [10] \" Dynamin I phosphorylation and the control of synaptic vesicle endocytosis. \" Smillie K. J. Cousin M. A. Biochem. Soc. Symp. 72:87-97(2005) [PubMed: 15649133] [Abstract]Cited for: REVIEW ON FUNCTION.