Phospho-STAT3(S727) Antibody

Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Developmental Biology; Microbiology; Signal Transduction; Phospho Antibodies; Viral process; Host-virus interaction; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; JAK-STAT signaling; Jak-STAT signaling KEGG

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. It mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.

RB5791

Affinity Purified Rabbit Polyclonal Antibody (Pab)

88068

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide