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Phospho-PDX1(T11) Antibody

Phospho-PDX1(T11) Antibody

Item no.	ABC-AP3669a
Manufacturer	Abcepta
Amount	400 ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies Immunofluorescence Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	IF, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	References for protein: 1.Nicolino,M., et.al., Diabetes 59 (3), 733-740 (2010) 2.Cai,J., et.al., J Mol Cell Biol 2 (1), 50-60 (2010) References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704].
NCBI	NP_000200.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pancreas/duodenum homeobox protein 1,PDX-1,Glucose-sensitive factor,GSF,Insulin promoter factor 1,IPF-1,Insulin upstream factor 1,IUF-1,Islet/duodenum homeobox-1,IDX-1,Somatostatin-transactivating factor 1,STF-1,PDX1,IPF1,STF1
Similar products	PDX-1, PDX1, STF1, GSF, IDX-1, IPF1, STF-1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, Somatostatin-transactivating factor 1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, Pancreas/duodenum homeobox protein 1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Developmental Biology; Metabolism; Signal Transduction; Phospho Antibodies
Manufacturer - Targets	This PDX1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T11 of human PDX1.
Bio Background	PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this protein are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB15204
Gene Name	PDX1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	30771
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:100 DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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