Comparison

CA9 Antibody (Center)

Item no. ABC-AP5000e
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, FC, IF
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CA9, G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, pMW1, CAIX, CA-IX, RCC-associated antigen G250
Available
Primary Accession
Q16790
Antigen Type
Synthetic Peptide
Application
IF, FC, WB
Bio Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.
Bio References
Grabmaier, K., et al., Oncogene 23(33):5624-5631 (2004).
Kaluzova, M., et al., Mol. Cell. Biol. 24(13):5757-5766 (2004).
Span, P.N., et al., Br. J. Cancer 89(2):271-276 (2003).
Hedley, D., et al., Clin. Cancer Res. 9(15):5666-5674 (2003).
Bui, M.H., et al., Clin. Cancer Res. 9(2):802-811 (2003).
Clonality
Polyclonal
Clone/Animal Names
RB18383
Gene ID
768
Gene Name
CA9
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Immunofluorescence analysis of CA9 Antibody (Center) with hela cells . 0.025 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.
Type image 1
IF
Dilution image 1
1:10~50
Legend image 2
Western blot analysis of CA9 antibody (Center) (Cat.# AP5000e) in Hela cell line lysates (35ug/lane). CA9 (arrow) was detected using the purified Pab.
Type image 2
WB
Dilution image 2
1:1000
Legend image 3
Flow cytometric analysis of hela cells using CA9 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3
FC
Dilution image 3
1:10~50
Isotype
Rabbit Ig
Calculated MW
49698
Antigen Region
113-143
Antigen Source
HUMAN
Target/Specificity
This CA9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-143 amino acids from the Central region of human CA9.
NCBI Accession
NP_001207.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

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