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BACE2 Antibody (Center)

BACE2 Antibody (Center)

Item no.	ABC-AP6121a
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Aging & Neurological Disorders Antibodies Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003). Basi, G., et al., J. Biol. Chem. 278(34):31512-31520 (2003). Barbiero, L., et al., Exp. Neurol. 182(2):335-345 (2003). Shi, X.P., et al., J. Biol. Chem. 278(23):21286-21294 (2003). Kondoh, K., et al., Breast Cancer Res. Treat. 78(1):37-44 (2003).
NCBI	NP_036237.2,NP_620476.1,NP_620477.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BACE2, AEPLC, ALP56, ASP21, Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, ASP1, DRAP, Asp 1, Beta-site APP cleaving enzyme 2
Available
Manufacturer - Category	Primary Antibodies; Cell Biology; Neuroscience
Manufacturer - Targets	This BACE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the Central region of human BACE2.
Bio Background	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB2187
Gene Name	BACE2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	56180
Antigen Source	HUMAN
Antigen Region	336-365
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide
Manufacturer - Alias	Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, ASP1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, DRAP, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, BACE2, AEPLC, ALP56, ASP21
Manufacturer - Similar	Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, ASP1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, DRAP, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, BACE2, AEPLC, ALP56, ASP21

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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