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MMP16 Antibody (N-term)

MMP16 Antibody (N-term)

Item no.	ABC-AP6200a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MMP-16, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP, MMP-X2, MMP16, MMPX2, Matrix metalloproteinase-16, 3424-
Available
Primary Accession	P51512
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene for MMP16 produces two transcripts, which encode a membrane-bound form and a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Bio References	Jung, M., et al., Prostate 55(2):89-98 (2003). Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999). Matsumoto, S., et al., Biochim. Biophys. Acta 1354(2):159-170 (1997). Sato, H., et al., Genomics 39(3):412-413 (1997). Mattei, M.G., et al., Genomics 40(1):168-169 (1997).
Clonality	Polyclonal
Clone/Animal Names	RB2031
Gene ID	4325
Gene Name	MMP16 (HGNC:7162)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	MMP16 Antibody (E169) (Cat. #AP6200a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the MMP16 antibody detected the MMP16 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	O35548; Q9WTR0; NP_072086
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	69521
Antigen Region	154-183
Antigen Source	HUMAN
Target/Specificity	This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human MMP16.
NCBI Accession	NP_005932.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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