Comparison

MMP25 Antibody (C-term)

Item no. ABC-AP6206a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Matsuda, A., et al., J. Biol. Chem. 278(38):36350-36357 (2003).
Velasco, G., et al., Cancer Res. 60(4):877-882 (2000).
Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Pei, D., Cell Res. 9(4):291-303 (1999).
Kojima, S., et al., FEBS Lett. 480 (2-3), 142-146 (2000).
NCBI NP_071913.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Matrix metalloproteinase-25,MMP-25,3424-,Leukolysin,Membrane-type matrix metalloproteinase 6,MT-MMP 6,MTMMP6,Membrane-type-6 matrix metalloproteinase,MT6-MMP,MT6MMP,MMP25,MMP20,MMPL1,MT6MMP
Similar products MMP25, MMP20, MMPL1, MT6MMP, Matrix metalloproteinase-25, Leukolysin, Membrane-type matrix metalloproteinase 6, Membrane-type-6 matrix metalloproteinase, MT6-MMP, 3424-, MMP-25, MTMMP6, MT-MMP 6
Available
Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Signal Transduction
Manufacturer - Targets
This MMP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP25.
Bio Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP2 but has been renamed matrix metalloproteinase 25 (MMP25).
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB2043
Gene Name
MMP25
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Calculated Molecular Weight
62554
Antigen Source
HUMAN
Antigen Region
470-499
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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