MMP7 Antibody (Center)

Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

RB2092

Purified Rabbit Polyclonal Antibody (Pab)

29677

117-146

IF: 1:10~50
WB: 1:1000
IHC-P: 1:50~100