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APP Antibody (C-term)

APP Antibody (C-term)

Item no.	ABC-AP6306B
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Adenocarcinoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Borroni, B., et al., Arch. Neurol. 60(12):1740-1744 (2003). Lleo, A., et al., J. Biol. Chem. 278(48):47370-47375 (2003). Zhou, Y., et al., Science 302(5648):1215-1217 (2003). Murakami, K., et al., J. Biol. Chem. 278(46):46179-46187 (2003). Kim, J.Y., et al., Biochem. Biophys. Res. Commun. 310(3):904-909 (2003).
NCBI	NP_000475.1,NP_001129488.1,NP_001129601.1,NP_001129602.1,NP_001129603.1,NP_001191230.1,NP_001191231.1,NP_001191232.1,NP_958816.1,NP_958817.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	APP, A4, AD1, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, N-APP, Soluble APP-alpha, Soluble APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, CVAP, Beta-APP40, Beta-amyloid protein 40, PN-II, C31, C80, C83, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Amyloid intracellular domain 50, Amyloid intracellular domain 57, Amyloid intracellular domain 59, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), S-APP-alpha
Available
Manufacturer - Category	Primary Antibodies; Neuroscience; Inflammasome
Manufacturer - Targets	This APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 736-770 amino acids from the C-terminal region of human APP.
Bio Background	APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP6 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB05013-05014
Gene Name	APP
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Pr, M, Pig, Rat
Calculated Molecular Weight	86943
Antigen Source	HUMAN
Antigen Region	736-770
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:1000
Antigen Type	Synthetic Peptide
Manufacturer - Alias	Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31, APP, A4, AD1
Manufacturer - Similar	Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31, APP, A4, AD1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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