Tuberin (TSC2) Antibody (S1798)

Primary Antibodies; Cell Biology; Metabolism; Signal Transduction; Viral process; Host-virus interaction

Mutations in TSC2 lead to tuberous sclerosis complex. This protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

RB13393

Affinity Purified Rabbit Polyclonal Antibody (Pab)

200608

1776-1805

IF: 1:10~50
WB: 1:1000
WB: 1:1000
WB: 1:1000
IHC-P: 1:10~50