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MLF1 Antibody (N-term)

MLF1 Antibody (N-term)

Item no.	ABC-AP6716a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MLF1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1
Available
Primary Accession	P58340
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Bio References	Li, Z.F., J. Neurol. Sci. 264 (1-2), 77-86 (2008) Yoneda-Kato, N., EMBO J. 24 (9), 1739-1749 (2005)
Clonality	Polyclonal
Clone/Animal Names	RB18642
Gene ID	4291
Gene Name	MLF1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of MLF1 Antibody (N-term) (Cat. #AP6716a) in mouse heart tissue lysates (35ug/lane). MLF1 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of MLF1 (arrow) using rabbit polyclonal MLF1 Antibody (N-term) (Cat. #AP6716a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MLF1 gene.
Type image 2	WB
Dilution image 2	1:1000
Isotype	Rabbit Ig
Calculated MW	30627
Antigen Region	35-62
Antigen Source	HUMAN
Target/Specificity	This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human MLF1.
NCBI Accession	NP_001123628.1; NP_001123629.1; NP_001182361.1; NP_001182362.1; NP_001182363.1; NP_071888.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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